Paoli Dam began her acting career in the early 2000s, making her debut in the Bengali film industry with the movie "Lokkhi Chabiyal" in 2006. However, it was her breakthrough performance in the 2010 film "Bhalo Bhashabi" that gained her widespread recognition. Her portrayal of a strong-willed and independent woman in the movie earned her critical acclaim and established her as a leading lady in Bengali cinema.