"Nadunisi Naaygal" translates to "Midnight Dogs" in English. The movie revolves around the life of two male protagonists, Kathiresan (played by Sibiraj) and Aadhavan (played by Arjun). Kathiresan, a bike enthusiast, and Aadhavan, a software engineer, lead seemingly ordinary lives. However, their paths intertwine in unexpected ways, leading to a thrilling narrative.